Sr Research Asst

Institution:  Tan Tock Seng Hospital
Family Group:  Allied Health

JOB SUMMARY

We are seeking a motivated and skilled Senior Research Assistant to join our team at the Infectious Disease Research Laboratory. The ideal candidate will have a strong background in bacteriology, excellent laboratory skills, and the ability to work independently and collaboratively on various research projects. This is an excellent opportunity for a detail-oriented individual to contribute to impactful research in infectious diseases.

 

MAIN DUTIES AND RESPONSIBILITIES

 

  • Assist in the design, execution and analysis of research related to Bacteriology.
  • Preparation, handling and processing of clinical samples.
  • Advanced microbial techniques such as bacterial culture techniques (aerobic and anaerobic), isolation and identification of bacterial strains by colony morphology and MALDI-TOF mass spectrometry, and use of selective and differential media.
  • Antimicrobial Susceptibility Testing (AST) – Performing standard methods such as disk diffusion, broth microdilution, and E-test. Analyzing and interpreting antibiotic susceptibility profiles.
  • Broth Dilution Techniques – Preparation and dilution of antibiotic solutions. Evaluating minimum inhibitory concentrations (MIC).
  • Design and perform molecular assays, including DNA/RNA extraction, PCR/qPCR, gel electrophoresis and Whole Genome Sequencing (WGS).
  • Assist in data analysis and management, preparing reports, and publications.
  • Assist in the development, implementation and revision of standard operating procedure(s) and risk assessments for department.
  • Assist in planning of study logistics, workflow, documentation and execution of new studies, liaising with internal and external parties as needed.
  • Work closely with researchers and other team members to support ongoing projects.
  • Train and mentor junior research assistants and interns in laboratory techniques and safety practices.
  • Assist in general laboratory maintenance and perform other duties as directed by supervisors and HOD, including work areas not mentioned here.

 

JOB REQUIREMENTS

 

  • Bachelor’s or Master’s degree in Microbiology, Bacteriology, or a related field.  
  • Minimum of 3-5 years of laboratory experience in bacteriology or microbiology clinical research.
  • Proficiency in bacteriology laboratory techniques, including culture, identification, AST, and broth dilution.
  • Experienced in working with common hospital bacteria such as MRSA, C. diff, E.coli, Pseudomonas aeruginosa, Klebsiella species, Enterococcus species and Acinetobacter baumannii.
  • Hands-on experience with MALDI-TOF mass spectrometry is preferred.
  • Familiarity with whole genome sequencing methodologies and bioinformatics analysis tools.
  • Strong analytical skills and attention to detail.
  • Good organizational skills and able to handle multiple tasks simultaneously.
  • Proficient in Microsoft Office Suite (Word, Excel, PowerPoint).
  • Excellent communication and interpersonal skills.
  • Ability to work independently and as part of a team.